[7][8][9], Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. Phthalic anhydride reacts violently with CuO at elevated temperatures [Park, Chang-Man, Richard J. Sheehan. I.K. [17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. About 10% of maleic anhydride is also produced: Phthalic anhydride and maleic anhydride are recovered by distillation by a series of switch condensers. PubChem Substance ID 24859242. It is a principal commercial form of phthalic acid. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. University of Georgia, Athens, GA 30602. Hydrolysis by hot water forms ortho-phthalic acid:[13]. Encyclopedia of Reagents for Organic Synthesis. It was the first anhydride of a dicarboxylic acid to be used commercially. EPA has determined that phthalic anhydride is a Hydrolysis of anhydrides is not typically a reversible process. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year.[4]. Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg (3), and water solubility, 6965 mg/L (4). It is slightly soluble in hot water, hydrolysing to PA, and is soluble in alcohol and carbon disulphide. Phthalic anhydride is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. Phthalic anhydride is the organic compound with the formula :-C6H4(CO)2O. 100% Phthalic Anhydride 85‐44‐9 4. PA is soluble in alcohol and carbon disulphide. Vanadium pentoksida (V2O5) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen molekuler. Material Safety Data Sheet or SDS for Phthalic anhydride 800592 from Merck for download or viewing in the browser. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Phthalic anhydride has another major use in the production of polyester resins and other minor uses in the production of alkyd resins used in paints and lacquers, certain guys, insect repellents, and urethane polyester polyols. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Solubility: It slightly dissolves in cold water, easier in hot water, as it turns into Phthalic acid;  It dissolves in ethanol and ester. Volatilization of phthalic anhydride from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 1.7X10-8 atm-cu m/mole (SRC) based upon its vapor pressure, 5.17X10-4 mm Hg (5), and water solubility, 6000 mg/L (6). Phthalic anhydride is a common laboratory chemical, Pthalic anhydride has been shown to be esterified with primary alcohols at room temperature. Early procedures involved liquid-phase mercury-catalyzed oxidation of naphthalene. The solubility of phthalic anhydride was measured at 283–313 K under atmospheric pressure in ethyl acetate, n -propyl acetate, methyl acetate, acetone, 1,4-dioxane, n -hexane, n -butyl acetate, cyclohexane, and dichloromethane. Logistics services are available in the United States. Acid anhydrides are also used as plasticizers for PVC and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. 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